A New Macrolide from a Marine-derived Fungus Aspergillus sp.

作者：Bao Jie; Xu Xin Ya; Zhang Xiao Yong; Qi Shu Hua^*

来源：Natural Product Communications, 2013, 8(8): 1127-1128.

• Aspergillus sp.
• Marine-derived fungus
• Macrolide
• Antiviral activity

A new 16-membered macrolide named aspergillide D (1), along with six known compounds, including two polyketones (2-3) and four alkaloids (4-7), were isolated from the culture broth of a marine-derived fungus Aspergillus sp. SCSGAF 0076. The structure of 1 was elucidated on the basis of NMR and mass spectra. Compound 5 showed an obvious inhibitory effect on influenza virus strains H1N1 and H3N2.

• 出版日期2013-8
• 单位中国科学院