A 6-year Follow-up survey of health status in middle-aged women with Turner syndrome

作者：Fjermestad Krister W^*; Naess Eva E; Bahr David; Gravholt Claus H

来源：Clinical Endocrinology, 2016, 85(3): 423-429.

DOI：10.1111/cen.13068

ObjectiveStudies suggest younger women with Turner syndrome (TS) have good quality of life. Less is known about everyday functioning in adults with TS. In a 6-year follow-up study, multiple areas of functioning were compared between TS women and controls. Design: Women with TS and controls were mailed a self-report survey 6 years after a baseline study.
PatientsFifty-seven women with TS (M age 406 111 years) and 101 controls (M age 388 106 years, ns) responded.
MeasurementsMeasures of background information, experienced life strain and presence/impact of health conditions were developed for this study. The QPS Nordic measured perceived workload challenges. The LiSat-9 measured life satisfaction. The Rosenberg Self-Esteem Scale measured self-esteem.
ResultsMore TS women lived alone, fewer had biological children, and more had adoptive children. TS women reported fewer sex partners and less sexual confidence. Controls had higher education. There was no difference in employment status. More TS women received disability pensions. TS women reported their work as more physically challenging, less positively challenging and requiring less knowledge skills. TS women experienced more life strain in school, adolescence and late working life. Controls reported higher overall life satisfaction, with no difference between samples on specific domains. TS women reported lower self-esteem. For TS women only, physical health at baseline predicted length of education and mental health at baseline predicted self-esteem.
ConclusionsWomen with TS face more challenges than controls on several domains of functioning. Early physical and mental health may influence later educational achievement and self-esteem for women with TS.

• 出版日期2016-9