A New Ellagic Acid Glycoside and DNA Topoisomerase IB Inhibitory Activity of Saponins from Putranjiva roxburghii

作者:Kumar Ashish; Chowdhury Somenath Roy; Chakrabarti Tulika; Majumdar Hemanta K; Jha Tarun; Mukhopadhyay Sibabrata*
来源:Natural Product Communications, 2014, 9(5): 675-677.
DOI:10.1177/1934578x1400900523

摘要

Chemical investigation of the stem bark and leaves of Putranjiva roxburghii has resulted in the isolation of a new ellagic acid glycoside (5) along with four saponins (1-4). The structures of the isolated compounds were established by detailed spectral analysis. Incidentally putranoside-A methyl ester (4) has been isolated for the first time from this species and the saponins (1-4) exhibited potent DNA topoisomerase IB inhibitory activity.

  • 出版日期2014-5