摘要

Continuous Annular Electro-Chromatography (CAEC) is a novel high performance continuous separation process for high value substances. A prototype is currently being developed in an EU-funded project(1). In this paper, we describe an iterative online optimization scheme for this process based upon a rigorous 2D model of the apparatus and the gradient modification technique that has been previously applied to the online optimization of batch chromatography by Gao and Engell [7].

  • 出版日期2011

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