Associations Between Day-by-Day Variability in Blood Pressure Measured at Home and Antihypertensive Drugs: The J-HOME-Morning Study

作者：Ishikura Kazuki; Obara Taku^*; Kato Tetsuo; Kikuya Masahiro; Shibamiya Taku; Shinki Takahiro; Ikeda Urara; Kobayashi Yuka; Metoki Hirohito; Mano Nariyasu; Kuriyama Shinichi; Ohkubo Takayoshi; Imai Yutaka

来源：Clinical and Experimental Hypertension, 2012, 34(4): 297-304.

DOI：10.3109/10641963.2012.681087

• hypertension
• blood pressure variability
• home blood pressure measurement
• antihypertensive drugs
• cross-sectional study

We identified the factors associated with home blood pressure (BP) variability in 1933 patients treated with hypertensive drugs (mean age, 67 years; women, 55%). Multivariate regression analysis showed that female gender, advanced age, home BP value, and home heart rate variability were positively associated with home BP variability, whereas home heart rate, body mass index, and duration of antihypertensive treatment were negatively associated with home BP variability. Moreover, not being medicated with amlodipine and being medicated with angiotensin II receptor blockers were associated with increased home systolic BP variability only among patients who were treated for less than 12 months.

• 出版日期2012