Water-Soluble Tb3+ and Eu3+ Complexes with Ionophilic (Ionically Tagged) Ligands as Fluorescence Imaging Probes

作者：Diniz Julia R; Correa Jose R; Moreira Daniel de A; Fontenele Rafaela S; de Oliveira Aline L; Abdelnur Patricia V; Dutra Jose D L; Freire Ricardo O; Rodrigues Marcelo O^*; Neto Brenno A D

来源：Inorganic Chemistry, 2013, 52(17): 10199-10205.

DOI：10.1021/ic4017678

This article describes a straightforward and simple synthesis of ionically tagged water-soluble Eu3+ and Tb3+ complexes (with ionophilic. ligands) applied for bioimaging of invasive mammal cancer cells (MDA-MB-;23 1). Use. of the task specific ionic. liquid 1-methyl-3-Cirboxymethyl imidazoliurn chloride : (MAT Cl) as the ionophilic. ligand tagged). proved to be a simple, elegant, and efficient Strategy to obtain highly fluorescent water soluble En(3+) (EuMAI) and Tb3+(TbMAI) complexes, TbMAI showed an intense bright green, fluorescence emission selectively staining endoplasmic: reticulum of MDA-MB=231 cells:

• 出版日期2013-9-2