An environmental friendly approach for the synthesis of highly substituted imidazoles using Bronsted acidic ionic liquid, N-methyl-2-pyrrolidonium hydrogen sulfate, as reusable catalyst

作者：Shaterian Hamid Reza^*; Ranjbar Mohammad

来源：Journal of Molecular Liquids, 2011, 160(1): 40-49.

DOI：10.1016/j.molliq.2011.02.012

• N-methyl-2-pyrrolidonium hydrogen sulfate
• 2,4,5-trisubstituted imidazoles
• 12,4,5-tetrasubstituted imidazoles
• Solvent-free
• Ionic liquid
• Catalyst

Bronsted acidic ionic liquid, N-methyl-2-pyrrolidonium hydrogen sulfate, has been used as an efficient and reusable catalyst for the one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles under thermal solvent-free conditions in excellent yields.

• 出版日期2011-4-15