Pathomorphological and Immunohistochemical Findings of Cystic Mucinous Hyperplasia of the Gall Bladder

作者：Alcigir M E^*; Polat I M; Coskan A S; Vural S A; Vural M R

来源：Israel Journal of Veterinary Medicine, 2013, 68(4): 225-229.

• Dog
• gall bladder
• cystic mucinous hyperplasia
• pathomorhology
• immunohistochemistry

A case of cystic mucinous hyperplasia is described in 5 years old, female, German Shepherd dog. Macroscopically the gall bladder was distended. There were multiple 0.1-0.3 cm size cystic papillary structures in many areas of gall bladder. In addition a 16 cm diameter paraovarian cyst containing serous fluid was detected in the cranial aspect of left ovary. Tissues were processed routinely and stained with haematoxylin-eosin (H%26E) and Periodic Acid Shiff (PAS) stains. The gall bladder cysts contained a mucinous secretion and were lined with cuboidal epithelium. Immunohistochemically, TGF- beta 1, HER2 and Cx43 markers were mildly positive in cytoplasm of the gall bladder epithelial cells although there were no positive reactions with Ki67 and CEA markers.

• 出版日期2013-12