Luminescence enhancement effect for the determination of balofloxacin with balofloxacin-europium (III)-sodium dodecylbenzene sulfonate system

作者：Wang Lei^*; Guo Changchuan; Chu Zhijie; Jiang Wei

来源：Journal of Luminescence, 2009, 129(1): 90-94.

DOI：10.1016/j.jlumin.2008.08.006

• Balofloxacin
• Europium
• Determination
• Luminescence

A novel method of luminescence enhancement effect for the determination of balofloxacin (BLFX) was proposed. A new system of the BLFX-Eu3 -SDBS (sodium dodecylbenzene sulfonate) was investigated. It was found that SDBS significantly enhanced the luminescence intensity of the BLFX-Eu3 complex (about 20-fold). Under the optimized experimental conditions, the system exhibits an excellent linear relationship between the enhanced luminescence intensity and the concentration of BLFX over the range of 1.0 x 10(-8)-8.0 x 10(-7) mol L-1 with a correlation coefficient (R) of 0.9994. and the detection limit (3 sigma) of the method was determined as 2.0 x 10(-9) mol L-1. This method has been successfully applied for the determination of BLFX in pharmaceuticals and human urine/serum samples. Compared with most of the other methods reported, the rapid and simple procedure proposed in the text offers higher sensitivity, wider linear range, and better stability.

• 出版日期2009-1
• 单位山东大学