Antifungal Substances from Streptomyces sp A3265 Antagonistic to Plant Pathogenic Fungi

作者：Nguyen Van Minh; Woo E Eum; Kim Ji Yul; Kim Dae Won; Hwang Byung Soon; Lee Yoon Ju; Lee In Kyoung; Yun Bong Sik^*

来源：Mycobiology, 2015, 43(3): 333-338.

DOI：10.5941/MYCO.2015.43.3.333

• Biocontrol agent
• Damping-off
• Guanidylfungin
• Streptomyces sp A3265

In a previous study, we identified a Streptomyces sp., A3265, as exhibiting potent antifungal activity against various plant pathogenic fungi, including Botrytis cinerea, Colletotrichum gloeosporioides, and Rhizoctonia solani. This strain also exhibited a biocontrolling effect against ginseng root rot and damping-off disease, common diseases of ginseng and other crops. In this study, we isolated two antifungal substances responsible for this biocontrolling effect via Diaion HP-20 and Sephadex LH-20 column chromatography, medium pressure liquid chromatography, and high-performance liquid chromatography. These compounds were identified as guanidylfungin A and methyl guanidylfungin A by spectroscopic methods. These compounds exhibited potent antimicrobial activity against various plant pathogenic fungi as well as against bacteria.

• 出版日期2015-9