科研之友
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摘要
Highly aqueous dilutable microemulsions based on biocompatible materials were developed and structurally investigated. Phase diagrams were constructed for systems consisting of nonionic Tweens (20, 40, and blends of them), R-(+)-limonene, ethanol, water, and propylene glycol. The obtained phase diagrams reveal the formation of highly aqueous dilutable microemulsions along certain dilution lines in the surfactant-rich region. Two phase transitions of the investigated systems were detected by conductivity measurements, from water in oil (w/o) to bicontinuous and to the oil in water (o/w), without phase separation. Interfacial properties and the dynamic structure of the surfactant monolayer were studied by electron paramagnetic resonance spectroscopy. It was observed that the mobility of the spin probe and the rigidity of the membrane are affected by increasing aqueous content and by the type of surfactant. Dynamic light scattering (DLS) measurements were performed in o/w microemulsions for different aqueous content, and oil droplet diameters in the range of 8.2 to 17.4 nm were observed.
- 出版日期2015-4
