科研之友
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摘要
An efficient and environment-friendly method for the synthesis of 1,3-oxazine derivatives has been developed using the ultrasound-mediated condensation of 2-naphthol with formaldehyde and primary amines under solvent-free condition at room temperature in the presence of BF3-SiO2 to give the desired product in good to excellent yield. This procedure provides several advantages over current methods including a simple work-up, cost effectiveness, a reusable catalyst and shorter reaction times.
- 出版日期2012-7
