Alienusolin, a New 4 alpha-Deoxyphorbol Ester Derivative, and Crotonimide C, a New Glutarimide Alkaloid from the Kenyan Croton alienus

作者：Ndunda Beth; Langat Moses K^*; Wanjohi John M; Midiwo Jacob O; Kerubo Leonidah O

来源：Planta Medica, 2013, 79(18): 1762-1766.

DOI：10.1055/s-0033-1351044

• 4-deoxyphorbol ester
• glutarimide alkaloid
• Croton alienus
• Euphorbiaceae

Two novel compounds, alienusolin, a 4 alpha-deoxyphorbol ester (1), crotonimide C, a glutarimide alkaloid derivative (2), and ten known compounds, julocrotine (3), crotepoxide (4), monodeacetyl crotepoxide (5), dideacetylcrotepoxide, (6), beta-senepoxide (7), alpha-senepoxide (8), (+)-(2S, 3R-diacetoxy-1-benzoyloxymethylenecyclohex-4,6-di-ene (9), benzyl benzoate (10), acetyl aleuritolic (11), and 24-ethylcholesta-4,22-dien-3-one (12) were isolated from the Kenyan Croton alienus. The structures of the compounds were determined using NMR, GCMS, and HRESIMS studies.

• 出版日期2013-12