Association Between Lichen Sclerosus and Celiac Disease: A Report of Three Pediatric Cases

作者:Jacobs Lauren; Gilliam Amy; Khavari Nasim*; Bass Dorsey
来源:Pediatric Dermatology, 2014, 31(6): E128-E131.
DOI:10.1111/pde.12402

摘要

The prevalence of celiac disease (CD) is increasing and may be as high as 1% of the US population. The typical presentation of CD generally includes gastrointestinal symptoms, but more individuals are presenting with extraintestinal manifestations. A wide variety of dermatologic associations have been described with CD, including alopecia, dermatitis herpetiformis, and enamel hypoplasia. In this report we describe three girls with CD who presented with hypopigmented skin lesions and pruritus in the perivaginal and perianal areas, consistent with the diagnosis of lichen sclerosus (LS). All three presented within 1 year to the same practitioner. To our knowledge, this association has not previously been explored in the literature. These cases elucidate a possible relationship between CD and LS.

  • 出版日期2014-12