科研之友
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摘要
As effective radical scavengers in vivo, superoxide dismutases (SODs) have the antioxidant, anti-inflammation and anti-aging functions, and have been applied in clinical treatments as drugs. Therefore, there is still an increasing interest in design and development of artificial SODs for potential application. In this article, a brief introduction about the research achievement of SOD mimics and their biomedical activities during past decade is shown. Our attention focuses on the relation between the structure and biological function of Cu, Zn-SOD mimics as well as the bio-activity and application of Mn-SOD mimics in medicine.
