Seco-pregnane glycosides from the stems of Epigynum auritum

作者:Gao, Fei; Yao, Yuan-Cheng; Wan, Zong; Cai, Sheng-Bao; Fan, Jian; Zhao, Tian-Rui; Cao, Jian-Xin*; Cheng, Gui-Guang*
来源:Natural Product Research, 2017, 31(9): 1102-1105.
DOI:10.1080/14786419.2016.1263852

摘要

Chemical investigation of the stems of Epigynum auritum led to the isolation and identification of a novel 16,17-seco pregnane glycoside, epigynoside D, along with other three known compounds (2-4). The structure of compound 1 was elucidated by means of spectroscopic analysis, including HRESIMS, 1D and 2D NMR experiments. All isolated compounds were tested for their in vitro cytotoxic, immunological and anti-acetylcholinesterase activities. @@@ [GRAPHICS] @@@ .