Association of Interankle Systolic Blood Pressure Difference With Peripheral Vascular Disease and Left Ventricular Mass Index

作者：Su Ho Ming; Lin Tsung Hsien; Hsu Po Chao; Lee Wen Hsien; Chu Chun Yuan; Chen Szu Chia^*; Lee Chee Siong; Voon Wen Chol; Lai Wen Ter; Sheu Sheng Hsiung

来源：American Journal of Hypertension, 2014, 27(1): 32-37.

DOI：10.1093/ajh/hpt154

• ankle-brachial index
• blood pressure
• brachial-ankle pulse wave velocity
• hypertension
• left ventricular mass index
• interankle systolic blood pressure difference

BACKGROUND An interankle systolic blood pressure (SBP) difference has been associated with overall and cardiovascular mortality. We investigated whether an association existed between this difference and ankle-brachial index (ABI), brachial-ankle pulse wave velocity (baPWV), and echocardiographic parameters. %26lt;br%26gt;METHODS A total of 1,059 patients referred for echocardiographic examination were included in the study. The 4 limb blood pressures were measured simultaneously using an ABI-form device. %26lt;br%26gt;RESULTS We performed multivariate forward analysis to determine the factors associated with an interankle SBP difference 15mm Hg. An ABI %26lt; 0.9 (P %26lt; 0.001), high baPWV (P %26lt; 0.001), and increased left ventricular mass index (LVMI; P 0.004) were associated with an interankle SBP difference 15mm Hg. Also, the addition of an interankle SBP difference 15mm Hg to a model of clinical features could significantly improve the value in predicting ABI %26lt; 0.9 (P %26lt; 0.001) and increased LVMI (P 0.036). %26lt;br%26gt;CONCLUSIONS Our study demonstrated that ABI %26lt; 0.9, high baPWV, and increased LVMI were independently associated with an interankle SBP difference 15mm Hg. Also, an interankle SBP difference 15mm Hg could offer an extra benefit in identifying patients with ABI %26lt; 0.9 and increased LVMI beyond conventional clinical features. Hence, calculation of interankle SBP difference may provide additional information for identifying patients with peripheral vascular disease and increased LVMI.

• 出版日期2014-1