Drug Fever due to a Single Dose of Pantoprazole

作者:Schiller Dietmar*; Maieron Andreas; Schoefl Rainer; Donnerer Josef
来源:Pharmacology, 2014, 94(1-2): 78-79.
DOI:10.1159/000364781

摘要

Although proton pump inhibitors (PPI) are generally well tolerated, with most adverse effects being minor and self-limiting, there are singular reports on hypersensitivity immune reactions triggered by a PPI or its metabolites. Here we report a case of acute drug-induced fever with leukocytosis and a transient increase in CRP due to pantoprazole. This was apparently an idiosyncratic reaction (inflammatory fever), showing no cross-sensitivity towards esomeprazole.

  • 出版日期2014