Direct difunctionalization of alkenes with sulfinic acids and NBS leading to beta-bromo sulfones

作者：Wei, Wei; Liu, Xiaoxia; Yang, Daoshan; Dong, Ruimei; Cui, Ying; Yuan, Fei; Wang, Hua^*

来源：Tetrahedron Letters, 2015, 56(14): 1808-1811.

DOI：10.1016/j.tetlet.2015.02.043

• beta-Bromo sulfones
• Alkenes
• Sulfinic acids
• NBS
• Difunctionalization

A new and metal-free method has been developed for the synthesis of beta-bromo sulfones through the direct difunctionalization of alkenes with sulfinic acids and NBS. This protocol provides a simple, convenient and efficient approach to various beta-bromo sulfones in moderate to good yields with excellent selectivity, and especially does not require any catalyst or additive.

• 出版日期2015-4-1
• 单位曲阜师范大学