Drug-induced Immune Thrombocytopenia

作者：Chong Beng H^*; Choi Philip Young Ill; Khachigian Levon; Perdomo Jose

来源：Hematology-Oncology Clinics of North America, 2013, 27(3): 521-+.

DOI：10.1016/j.hoc.2013.02.003

• Drugs
• Thrombocytopenia
• Immune
• Antibodies

Thrombocytopenia is caused by immune reactions elicited by diverse drugs in clinical practice. The activity of the drug-dependent antibodies produces a marked decrease in blood platelets and a risk of serious bleeding. Understanding of the cellular mechanisms that drive drug-induced thrombocytopenia has advanced recently but there is still a need for improved laboratory tests and treatment options. This article provides an overview of the different types of drug-induced thrombocytopenia, discusses potential pathologic mechanisms, and considers diagnostic methods and treatment options.

• 出版日期2013-6