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摘要
A phytochemical investigation of the roots of Incarvillea arguta led to the isolation of secoarguterin (1), which is the first example of 5,6-secoiridoid. Its structure and absolute configuration was elucidated by extensive spectral analysis and total synthesis. Compound 1 showedmoderate inhibition against human colon cancer cells HCT116 with an IC50 value of 28.72 mu M.
- 出版日期2016
- 单位中国人民解放军第二军医大学; 上海医药工业研究院; 上海交通大学; 华东理工大学
