Activity and Recyclability Improvement Through Adjusting the Tethering Strategy for Pd-Catalyzed Suzuki-Miyaura Coupling Reaction of Aryl Chlorides

作者：Zhang, Jing-Fan; Wang, Mingda; Guo, Xu-Qing; Liu, Shu^*; Cao, Hui; Li, Yuan-Long; Zhou, Quan; Hou, Xiu-Feng

来源：Catalysis Letters, 2015, 145(12): 2001-2009.

DOI：10.1007/s10562-015-1609-1

• N-heterocyclic carbene
• Palladium
• Immobilization
• Suzuki-Miyaura reaction
• Aryl chlorides
• Catalyst recycling

Four mesoporous SBA-15-immobilized N-heterocyclic carbene (NHC) palladium catalysts with different nitrogen ligands were synthesized. The activity and recyclability of the catalysts were investigated in Suzuki-Miyaura cross-coupling reaction of typical aryl chlorides and arylboronic acids. Bulky NHC moiety was essential for efficiency, while tethering of nitrogen ligands on both support and NHC group could dramatically improve recyclability of the catalysts. The strategy offers an alternative strategy for designing highly efficient and recyclable immobilized catalysts. @@@ Mesoporous silica-immobilized palladium catalysts with the bulky N-heterocyclic carbene and tethered "throw-away"nitrogen ligands were found to be highly efficient and recyclable for Suzuki-Miyaura coupling reaction of inactive aryl chlorides.

• 出版日期2015-12
• 单位复旦大学; 中华人民共和国上海出入境检验检疫局