Molecular cloning of a gene encoding phospholipase D from the pathogenic and dimorphic fungus, Candida albicans

作者：Kanoh H^*; Nakashima S; Zhao YT; Sugiyama Y; Kitajima Y; Nozawa Y

来源：Biochimica et Biophysica Acta-Gene Structure and Expression, 1998, 1398(3): 359-364.

DOI：10.1016/S0167-4781(98)00067-0

• phospholipase D
• genomic DNA
• phylogenetic analysis
• (Candida albicans)

A phospholipase D gene (CaPLD) has been cloned from the Candida albicans genomic DNA library. The CaPLD is a member of a highly conserved gene family of PLD and has the highest homology to Saccharomyces cerevisiae PLD (SPO14) with an overall homology of 42%. Phylogenetic analysis indicated that fungus PLDs including CaPLD composed one of the three clusters of PLD genes.

• 出版日期1998-7-9