Application of C-18-modified mseoporous SBA-15 as the substrate for high performance liquid chromatography

作者：Gao F; Zhao JW; Zhang S; Zhou F; Jin W; Zhang XM; Yang PY^*; Zhao DY

来源：Chemical Journal of Chinese Universities, 2002, 23(8): 1494-1497.

• mesoporous silica
• SBA-15
• HPLC
• mercapto compound

C-18 functionalized mesoporous silica SBA-15 with a high surface area was applied in high performance liquid chromatography (HPLC) to separate small blomolocules: cysteine, glutathione, dopamine and 6-thiopurine. Compared to commercial available C-18 column, C-18-SBA-15 has a much higher surface area, which enhance,,, the capillary HPLC resolution by increasing molecular capacity factors. The uniform distributed mesopores in SBA-15 result in HPLC peaks narrower than that of commercial column. Mesoporous SBA-15 can be used as an excellent HPLC stationary phase for special applications for its low cost, easy synthesis and various group-modifications.

• 出版日期2002-8
• 单位复旦大学