A Pilot Study on Factors Involved with Work Participation in the Early Stages of Multiple Sclerosis

作者：Van der Hiele Karin^*; Middelkoop Huub A M; Ruimschotel Rob; Kamminga Noelle G A; Visser Leo H

来源：PLos One, 2014, 9(8): e105673.

DOI：10.1371/journal.pone.0105673

Background: Up to 30% of recently diagnosed MS patients lose their jobs in the first four years after diagnosis. Taking into account the personal and socio-economic importance of sustaining employment, it is of the utmost importance to examine factors involved with work participation.
Objective: To investigate differences in self-reported functioning in recently diagnosed MS patients with and without a paid job.
Methods: Self-reports of physical and cognitive functioning, depression, anxiety and fatigue were gathered from 44 relapsing-remitting MS patients diagnosed within 3 years.
Results: Patients with a paid job (57%) reported better physical functioning (p<0.001), better memory functioning (p = 0.01) and a lower physical impact of fatigue (p = 0.018) than patients without a paid job. Physical functioning was the main predictor of employment status in a logistic regression model. In those with a paid job better memory functioning (r = 0.54, p = 0.005) and a lower social impact of fatigue (r = -0.46, p = 0.029) correlated with an increased number of working hours.
Conclusion: Better physical functioning is the primary factor involved with increased work participation in early MS. Better self-reported memory functioning and less social fatigue were associated with increased working hours. These findings highlight the importance of battling these symptoms in the early stages of MS.

• 出版日期2014-8-25