Acid Catalyzed Solvent Free Synthesis of New 1-Acyl-4-benzhydryl Substituted Pyrazoles

作者:Sher Muhammad; Ahmed Ejaz; Kausar Tasneem; Riaz Nadia; Arshad Muhammad; Sharif Ahsan*; Intisar Azeem; Akhtar Javeed; Aamir Muhammad
来源:Journal of the Chemical Society of Pakistan, 2016, 38(6): 1203-1210.

摘要

A convenient, cost effective and environmentally benign methodology has been developed, which delivered fourteen new 1-acyl-4-benzhyrdyl substituted pyrazole derivatives under solvent free conditions. Target compounds were synthesized in good to excellent yields simply by grinding reactants in a pestle and mortar with catalytic amount of conc. H2SO4. All the newly formed compounds were fully characterized with the help of detailed spectroscopic techniques including FTIR, NMR and GC-MS.

  • 出版日期2016-12