科研之友
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摘要
Three fluorinated (F-19 or F-18) small molecules were evaluated as fluorescent or radiolabeled probes for A beta deposits in the brain. In vivo near-infrared imaging suggested that probe 4c could efficiently distinguish between transgenic mice and wild-type controls. Furthermore, the in vivo Cerenkov luminescence imaging with [F-18]4c showed modest differences between the two groups.
