Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation

作者：Danquah Welbeck; Meyer Schwesinger Catherine; Rissiek Bjoern; Pinto Carolina; Serracant Prat Arnau; Amadi Miriam; Iacenda Domenica; Knop Jan Hendrik; Hammel Anna; Bergmann Philine; Schwarz Nicole; Assuncao Joana; Rotthier Wendy; Haag Friedrich; Tolosa Eva; Bannas Peter; Boue Grabot Eric; Magnus Tim; Laeremans Toon; Stortelers Catelijne; Koch Nolte Friedrich

来源：Science Translational Medicine, 2016, 8(366): 366ra162.

DOI：10.1126/scitranslmed.aaf8463

<jats:p>Single-domain antibodies called nanobodies block P2X7, an inflammatory ion channel, reducing skin and kidney inflammation in mice.</jats:p>

• 出版日期2016-11-23