An Organic Field-effect Transistor with an Extended-gate Electrode Capable of Detecting Human Immunoglobulin A

作者：Minamiki Tsukuru; Minami Tsuyoshi^*; Sasaki Yui; Kurita Ryoji; Niwa Osamu; Wakida Shin ichi; Tokito Shizuo

来源：Analytical Sciences, 2015, 31(7): 725-728.

DOI：10.2116/analsci.31.725

• Organic field-effect transistor
• immunosensor
• label-free
• immunoglobulin A
• self-assembled monolayer

We herein report on the development of an extended-gate type organic field-effect transistor (OFET)-based immunosensor for the detection of human immunoglobulin A (IgA). The titration results of IgA exhibited shifts in the transfer characteristics of the OFET sensor device with increasing IgA concentration. A linear detection range from 0 to 10 mu g/mL was realized with a detection limit of 2.1 mu g/mL, indicating that the OFET-based immunosensor can be potentially applied to the monitoring of infectious diseases and psychological stress in daily life.

• 出版日期2015-7