Amniocentesis and viral risk (hepatitis B, C virus and HIV)

作者：Ducarme G^*; Ceccaldi P F; Bernuau J; Luton D

来源：Journal de Gynecologie Obstetrique et Biologie de la Reproduction, 2009, 38(6): 469-473.

DOI：10.1016/j.jgyn.2009.07.001

• Amniocentesis
• Hepatitis B
• Hepatitis C
• HIV
• Mother-to-infant transmission

Very few studies have property addressed to the risk of fetal hepatitis B (HBV), hepatitis C (HCV) or human immunodeficiency virus (HIV) infection through amniocentesis. For HVB, this risk is low. However, knowledge of the maternal. hepatitis B e antigen status is valuable in the counselling of risks associated with amniocentesis. For HCV, the risk is not well known but cannot be excluded. For HIV, it seems rational to propose a viral test before amniocentesis for patients with contamination's risk and to postpone the sampling in cases with positive results in order to obtain an undetectable HIV-1 RNA viral toad. For these reasons, it can be useful to analyse for each virus the benefit of amniocentesis and the risk of mother-to-infant transmission, and to inform the patient.

• 出版日期2009-10