Hereditary Multiple Exostosis

作者:Ryckx Andries*; Somers Jan F A; Allaert Lieven
来源:Acta Orthopaedica Belgica, 2013, 79(6): 597-607.

摘要

Hereditary Multiple Exostosis is an intriguing genetic condition with a clinical impact in the field of orthopaedics, paediatrics and oncology. %26lt;br%26gt;In this review we highlight the current knowledge about this condition from a clinical and scientific point of view. This gives us more insight into the molecular mechanisms and current models on which therapeutic agents are based. It allows for a multidisciplinary approach to the management of this complex condition. %26lt;br%26gt;There is currently no exact pathological model that can accurately describe all the findings in the research on Hereditary Multiple Exostosis. Promising treatments with blocking agents are currently under investigation.

  • 出版日期2013-12