A Forty Year Odyssey in Metallo-Organic Chemistry

作者：Nicholas Kenneth M^*

来源：Journal of Organic Chemistry, 2015, 80(14): 6943-6950.

DOI：10.1021/acs.joc.5b00982

In this invited Perspective, I provide a personal account highlighting several of my group's research contributions in metallo organic chemistry over the past 40 years. Our early work focused primarily in stoichiometric structure/reactivity of transition metal organic compounds and their use in organic synthesis. More recent efforts have centered on the discovery and development of new metal-catalyzed organic reactions via reactive metal organic intermediates. The major research findings that are described here include (1) propargyl-cobalt complexes as electrophilic agents for C-C and C-Nu coupling; (2) the activation of carbon dioxide by metal complexes; (3) metal-promoted C-H nitrogenation reactions; (4) oxo-metal catalyzed deoxygenation reactions; and (5) catalyst discovery via dynamic templating with substrate- and transition-state analogues.

• 出版日期2015-7-17