科研之友
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摘要
New onset or exacerbation of psoriasis vulgaris has been reported in a small number of patients after interferon (IFN)-a therapy. Herein, we report a case of generalized flare of pustular psoriasis induced by PEGylated IFN-a2b (PEG-IFN-a2b) in a 59-year-old woman with a 15-year history of pustular psoriasis and chronic hepatitis C. Interferon-a therapy was discontinued and the rash resolved after treatment with cyclosporin and systemic methylprednisolone. The potential side effect of PEG-IFN-a2b in inducing or exacerbating psoriasis should be kept in mind when treating patients with a history of psoriasis or pustular psoriasis.
- 出版日期2012-11
