科研之友
微信
新浪微博
Facebook
分享链接
摘要
Current approaches for the treatment of psoriasis with anti-cytokine therapies involve the blockade of TNE-alpha, or the p40 sub-unit of IL-12 and IL-23. However, the field is currently evolving to test more selective antagonists, such as anti-IL-23p19, IL-17 and other inflammatory cytokines. Here we discuss our current understanding of dendritic cell and T cell subsets that are relevant in psoriasis, and the pharmacologic strategies that temper their activity in this disease.
- 出版日期2011-5-15
