Acanthamoeba Keratitis in South India: A Longitudinal Analysis of Epidemics

作者：Lalitha Prajna; Lin Charles C; Srinivasan Muthiah; Mascarenhas Jeena; Prajna N Venkatesh; Keenan Jeremy D; McLeod Stephen D; Acharya Nisha R; Lietman Thomas M; Porco Travis C^*

来源：Ophthalmic Epidemiology, 2012, 19(2): 111-115.

DOI：10.3109/09286586.2011.645990

• Acanthamoeba
• Cornea
• Epidemic
• India
• Keratitis

Purpose: In light of the increased incidence of contact lens associated Acanthamoeba keratitis in recent years, this study analyzed longitudinal trends of its incidence among predominantly non-contact lens wearers in a high-volume referral center in South India.
Methods: A retrospective analysis of microbiology laboratory records at the Aravind Eye Hospital from 1988-2009 was performed. The Maximum Excess Events Test (MEET) was used to identify epidemics of Acanthamoeba keratitis.
Results: There were a total of 38,529 unique cases of infectious keratitis evaluated over this time period, of which 372 were culture-positive for Acanthamoeba. Only three cases (0.9%) of Acanthamoeba keratitis occurred among contact lens wearers. MEET identified unique Acanthamoeba keratitis epidemics in 1993 and 2002.
Conclusion: Discrete epidemics of Acanthamoeba keratitis occurred among a rural, non-contact lens wearing, population in South India in 1993 and 2002.

• 出版日期2012-4