AN EFFICIENT CONVERSION OF LYSINE TO 2-AMINOCAPROLACTAM

作者:Matsumoto Hiroshi; Kaiso Kouji; Kamimura Akio*
来源:Heterocycles, 2016, 92(2): 337-345.
DOI:10.3987/COM-15-13358

摘要

Lysine heated in wet MeOH at high-temperature was smoothly and efficiently converted to 2-aminocaprolactam, which is recognized as a potential intermediate for the preparation of bioactive compounds. The obtained 2-aminocaprolactam underwent very rapid racemization under these conditions. A kinetic study of the reaction was performed.

  • 出版日期2016-2-1

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