A ring-closing metathesis approach to secosteroidal macrocycles

作者：Ibrahim Ouali Malika^*; Zoubir Jamel; Romero Eugenie

来源：Tetrahedron Letters, 2011, 52(52): 7128-7131.

DOI：10.1016/j.tetlet.2011.10.108

• Secocholane
• Baeyer-Villiger oxidation
• Macrocyclization
• Ring-closing metathesis (RCM)

An efficient synthesis of secosteroidal macrocycles has been achieved via an oxidative ring-expansion/ring-opening sequence and a ring-closing metathesis reaction as the key steps.

• 出版日期2011-12-28