Multi-Walled Carbon Nanotubes as Matrix Solid-Phase Dispersion Extraction Adsorbent for Simultaneous Analysis of Residues of Nine Organophosphorus Pesticides in Fruit and Vegetables by Rapid Resolution LC-MS-MS

作者：Guan, Shu-xia^*; Yu, Zhi-gang; Yu, Hai-nan; Song, Chun-hong; Song, Zeng-qiang; Qin, Zhi

来源：Chromatographia, 2011, 73(1-2): 33-41.

DOI：10.1007/s10337-010-1840-2

• Column liquid chromatography
• RRLC-MS-MS
• Matrix solid-phase dispersion
• Multi-walled carbon nanotubes
• Food analysis
• Organophosphorus pesticides

A method for simultaneous analysis of residues of nine organophosphorus pesticides in fruit and vegetables has been developed. It involves matrix solid-phase dispersion (MSPD) for preconcentration before rapid resolution liquid chromatography-tandem mass spectrometry (RRLC-MS-MS). In the MSPD pre-concentration step, the adsorptive performance of multi-walled carbon nanotubes (MWCNT) as MSPD adsorbent and elution with four solvents were investigated; in the LC separation step, a rapid resolution high-throughout LC column was used with gradient elution. The results of the research showed that the linear correlation coefficients (r (2)) of the method for the nine target analytes varied between 0.9942 and 0.9996, mean recovery was in the range 71.2-102.8%, with relative standard deviations (RSD) 2.0-11.8%, and limits of detection were all below 0.2 mu g kg(-1). The method was used for simultaneous analysis of the nine pesticides in eight different fruit and vegetable samples.

• 出版日期2011-1
• 单位黑龙江大学; 哈尔滨学院; 东北石油大学