摘要
A novel ionic liquid modified NiO/CNTs carbon paste electrode (IL/NiO/CNTCPE) had been fabricated by using hydrophilic ionic liquid 1-methyl-3-butylimidazolium chloride [MBIDZ]Cl as a binder. The cyclic voltammogram showed an irreversible oxidation peak at 0.61 V (vs. Ag/AgClsat), which corresponded to the oxidation of morphine. Compared to common carbon paste electrode, the electrochemical response was greatly improved for morphine electrooxidation. This modified electrode exhibited a potent and persistent electron mediating behavior followed by well separated oxidation peaks of morphine and diclofenac. Detection limit of morphine was found to be 0.01 mu M using square wave voltammetry (SWV) method. The proposed sensor was successfully applied for the determination of morphine in human urine and pharmaceutical samples.
- 出版日期2014-2-1