Acute Effects of Isocaloric Meals with Different Fiber and Antioxidant Contents on Inflammatory Markers in Healthy Individuals

作者：Seixas Chaves Daniela Fojo; Solis Marina Yazigi; Gandin Paula; Benatti Fabiana Braga; Rodrigues Vinicius Lio; Paschoal Valeria; Naves Andreia; Lancha Antonio Herbert Jr

来源：Annals of Nutrition and Metabolism, 2013, 62(2): 164-168.

DOI：10.1159/000341407

• Antioxidants
• Diet
• Fiber
• Inflammation

Chronic inflammation contributes to the pathophysiology of many chronic diseases. Dietary fibers and antioxidants may exert anti-inflammatory effects. The objective of this study was to determine whether meals with different fibers and antioxidants may elicit a different response in inflammatory markers in healthy volunteers. On 3 separate days, subjects (n = 8) consumed one of three isocaloric meals with different antioxidant (vitamin E, selenium and beta-carotene) and fiber content (high, intermediate and low) in a randomized crossover design. Blood samples were collected at different times: 0 min (before the meal), and 30 and 240 min after the meal. Plasma interleukin (IL)-6, IL-10, tumor necrosis factor (TNF)-alpha, glucose and insulin content were evaluated at each time point. There were no significant differences for any of the parameters at baseline. Furthermore, plasma levels of TNF-alpha, IL-6 and IL-10 were unchanged at the 30- and 240-min time points whatever meal consumed. Moreover, the cytokine responses to glucose and insulin intake were not significantly different between experimental conditions. In conclusion, isocaloric meals with different fiber, beta-carotene, vitamin E and selenium contents do not acutely affect inflammatory markers in healthy young males.

• 出版日期2013