An Efficient Molecular Scaffold Exhibiting Fluorescence "Turn-On" Response for Cyanide and HCN

作者：Gupta Ramesh C; Dwivedi Sushil K; Ali Rashid; Misra Arvind

来源：ChemistrySelect, 2018, 3(7): 2025-2031.

DOI：10.1002/slct.201702901

<jats:title>Abstract</jats:title><jats:p>The present work describes design and synthesis of a biphenylaldimine derivative, probe <jats:bold>2</jats:bold> as an efficient molecular scaffold. The probe <jats:bold>2</jats:bold> showed good photophysical behavior and upon interaction with anions and gases showed high selectivity and sensitivity for CN<jats:sup>‐</jats:sup> anion and HCN gas through a reaction based chemodosimeter approach with limit of detection 24 ppb and 7 ppm, respectively. The change in optical behavior of the probe is attributed to intramolecular charge transfer (ICT) mechanism. Probe <jats:bold>2</jats:bold> displayed enhanced emission, “<jats:italic>turn‐on</jats:italic>” due to the formation of a new biphenyl oxazole derivative <jats:bold>4</jats:bold> in the medium along with change in color of the medium which was sensitive to the naked‐eyes. The mechanism of interaction between probe and cyanide anion have been confirmed by the <jats:sup>1</jats:sup>H NMR, <jats:sup>13</jats:sup>C NMR and HRMS spectral data analysis. The molecular probe <jats:bold>2</jats:bold> has been successfully utilized to detect cyanide (CN<jats:sup>‐</jats:sup>) and HCN gas in solution and on test paper strips.</jats:p>

• 出版日期2018-2-21