Adherence to a Healthy Diet According to the World Health Organization Guidelines and All-Cause Mortality in Elderly Adults From Europe and the United States

作者：Jankovic Nicole^*; Geelen Anouk; Streppel Martinette T; de Groot Lisette C P G M; Orfanos Philippos; van den Hooven Edith H; Pikhart Hynek; Boffetta Paolo; Trichopoulou Antonia; Bobak Martin; Bueno de Mesquita H B; Kee Frank; Franco Oscar H; Park Yikyung; Hallmans Goran; Tjonneland Anne; May Anne M; Pajak Andrzej; Malyutina Sofia; Kubinova Ruzena; Amiano Pilar; Kampman Ellen; Feskens Edith J

来源：American Journal of Epidemiology, 2014, 180(10): 978-988.

DOI：10.1093/aje/kwu229

• aging
• cohort
• Consortium on Health and Ageing: Network of Cohorts in Europe and the United States
• diet
• longevity
• meta-analysis

The World Health Organization (WHO) has formulated guidelines for a healthy diet to prevent chronic diseases and postpone death worldwide. Our objective was to investigate the association between the WHO guidelines, measured using the Healthy Diet Indicator (HDI), and all-cause mortality in elderly men and women from Europe and the United States. We analyzed data from 396,391 participants (42% women) in 11 prospective cohort studies who were 60 years of age or older at enrollment (in 1988-2005). HDI scores were based on 6 nutrients and 1 food group and ranged from 0 (least healthy diet) to 70 (healthiest diet). Adjusted cohort-specific hazard ratios were derived by using Cox proportional hazards regression and subsequently pooled using random-effects meta-analysis. During 4,497,957 person-years of follow-up, 84,978 deaths occurred. Median HDI scores ranged from 40 to 54 points across cohorts. For a 10-point increase in HDI score (representing adherence to an additional WHO guideline), the pooled adjusted hazard ratios were 0.90 (95% confidence interval (CI): 0.87, 0.93) for men and women combined, 0.89 (95% CI: 0.85, 0.92) for men, and 0.90 (95% CI: 0.85, 0.95) for women. These estimates translate to an increased life expectancy of 2 years at the age of 60 years. Greater adherence to the WHO guidelines is associated with greater longevity in elderly men and women in Europe and the United States.

• 出版日期2014-11-15