Antiviral effect of maraviroc in semen: a case report

作者：Pasquier Christophe^*; Moinard Nathalie; Saune Karine; Daudin Myriam; Trancart Stephanie; Massip Patrice; Izopet Jacques; Bujan Louis

来源：Antiviral Therapy, 2012, 17(5): 933-936.

DOI：10.3851/IMP2038

We describe the antiviral effect of maraviroc in a patient who had been shedding high levels of HIV-1 in seminal fluid for three years despite an undetectable blood plasma viral load. Adding maraviroc to HAART stopped the seminal shedding. We discuss the mechanisms involved and the effect on sexual transmission.

• 出版日期2012