Allylic and benzylic oxidation reactions with sodium chlorite

作者：Silvestre Samuel M; Salvador Jorge A R^*

来源：Tetrahedron, 2007, 63(11): 2439-2445.

DOI：10.1016/j.tet.2007.01.012

• sodium chlorite
• allylic oxidation
• benzylic oxidation
• transition-metal free

Various allylic and benzylic substrates were selectively oxidized to the corresponding enones in good yields using sodium chlorite, either in combination with tert-butyl hydroperoxide in stoichiometric conditions, or associated with N-hydroxyphthalimide as catalyst. These oxidation reactions were effectively and economically performed under mild, transition-metal free conditions and therefore the dual challenge of cost effectiveness and benign nature of the processes was met with.

• 出版日期2007-3-12