A simple fabrication of Ag-nanowires@TiO2 core-shell nanostructures for the construction of mediator-free biosensor

作者：Liu Hui^*; Dong Xiaonan; Duan Congyue; Zhu Zhenfeng

来源：Journal of Solid State Electrochemistry, 2015, 19(2): 543-548.

DOI：10.1007/s10008-014-2550-8

• Cyclic voltammetry
• Biosensors
• Core-shell structure
• Nanocomposites

One-dimensional Ag-nanowires@TiO2 core-shell nanostructures (ANTNs) have been synthesized via a simple solvent thermal method and employed to immobilize hemoglobin (Hb) in order to fabricate a mediator-free biosensor. Immobilized Hb on ANTNs protected by nafion film exhibited good bioactivity, stability, and remarkable electron transfer rate because of its unique core-shell structure and compose. The morphology and structure of the ANTNs were characterized by scanning electron microscopy (SEM) and X-ray diffraction (XRD). Electrochemical measurements revealed that the ANTNs were an immobilization support with biocompatibility for enzymes, affording good enzyme stability and bioactivity. Due to the unique Ag-nanowires@TiO2 core-shell nanostructures, the resulting biosensor displayed good performance for the detection of H2O2, with both a low detection limit of 1.3 mu M and a wide linear range of 4-152 mu M, as well as a fast response and excellent long-term stability.

• 出版日期2015-2
• 单位陕西科技大学