Different types of alcoholic beverages and incidence of metabolic syndrome and its components in a Mediterranean cohort

作者：Barrio Lopez Maria T; Bes Rastrollo Maira; Sayon Orea Carmen; Garcia Lopez Martin; Fernandez Montero Alejandro; Gea Alfredo; Martinez Gonzalez Miguel A^*

来源：Clinical Nutrition, 2013, 32(5): 797-804.

DOI：10.1016/j.clnu.2012.12.002

• Metabolic syndrome
• Alcohol consumption
• Incidence
• Cohort

Background %26 aims: We prospectively assessed the association between alcohol consumption and the incidence of Metabolic Syndrome (MS) in a Mediterranean cohort. %26lt;br%26gt;Methods: We included 8103 (mean age: 35.4 years) University graduates free of any MS criteria and followed-up during %26gt;= 6 years. Alcohol consumption was collected with a validated 136-item food frequency questionnaire. New-onset cases of MS were defined according to the updated harmonizing criteria. %26lt;br%26gt;Results: We observed 341 incident cases of MS. Consumers of %26gt;= 7 drinks/wk presented a significantly higher risk of developing MS (aOR: 1.80; 95% CI: 1.22-2.66; p %26lt; 0.001) compared with non-drinkers. In addition, alcohol drinkers (%26gt;= 7 drinks/wk) had higher risk of hypertriglyceridemia (aOR: 2.07; 95% CI: 1.46-2.93) and impaired fasting glucose (aOR: 1.54; 95% Cl: 1.16-2.04). Beer consumption was associated with higher risk for MS (p for trend = 0.027) and higher risk of hypertriglyceridemia (aOR: 1.81; 95% CI: 1.02-3.20), but with lower risk of low HDL-cholesterol criterion (aOR: 0.21; 95% CI: 0.05-0.89) for %26gt;= 7 drinks/wk versus no consumption. Non-significant association was observed between wine or liquor consumption and MS. %26lt;br%26gt;Conclusions: Consumption of at least seven alcoholic drinks per week was associated with a higher risk of developing MS among subjects initially free of any MS criteria.

• 出版日期2013-10