Allosteric anion binding controlled by infrared irradiation: Light-triggered chromogenic sensing of iodide in aqueous solution

作者：Qi, Qiong; Lin, Ruolin; Chen, Xiaoyu; Li, Shunhua^*

来源：Sensors and Actuators B: Chemical , 2016, 222: 551-555.

DOI：10.1016/j.snb.2015.08.102

• Allosterism
• Molecular recognition
• Iodide
• Sensors
• Colorimetric detection

Allosteric molecular sensing, which makes a synthetic receptor work like a biological signal transduction system, is a challenging topic attracting intense research interest. In this manuscript, we report the first allosteric chemosensor that can be activated and controlled by infrared (IR) irradiation. As a very important structural element in the maintenance and regulation of protein function, disulfide bond (DSB) was employed as the photoactivatable hinge of a homotropic anion receptor based on disulfide-bridged binuclear silver(I) complexes. Because of the light-driven rotation of DSB, this biomimetically designed receptor shows a unique dynamic color response to iodide in aqueous solution under IR irradiation, which is distinctly different from what occurs in the dark. As a consequence, specific colorimetric detection of iodide in aqueous solution can be well established at the micromolar concentration level. Our study exemplifies a brand-new molecular sensing mode for anions. Furthermore, it opens a new way to operate disulfide bond as an optical switch, which may lead to important applications in chemical biology.

• 出版日期2016-1
• 单位厦门大学