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摘要
Graphical representation of protein sequence is to provide intuitive overall graphs as well as useful insights for performing large-scale analysis. Some methods have been proposed to analyze the similarities/dissimilarities among different sequences. Here, we consider a novel 3D graphical representation of protein sequences. It is based on a substitution matrix and the frequency of the 20 common amino acids. According to this representation, we give a 2D distance formula to calculate the distance of different protein sequences for similarity analysis. Finally, the proposed method is used to predict protein cellular localization.
- 出版日期2014-3
- 单位湖南大学
