A Novel and One-Pot Multicomponent Approach to the Synthesis of Dihyroindeno[1,2-b]pyrroles and Indeno[2 ',1 ':4,5]pyrrolo[1,2-a]-Fused 1,3-Diazaheterocycles

作者：Alizadeh Abdolali^*; Zarei Ameneh; Rezvanian Atieh

来源：Synthesis (Germany), 2011, 2011(3): 497-501.

DOI：10.1055/s-0030-1258383

• 1,1-bis(methylthio)-2-nitroethene
• ninhydrin
• indeno[1,2-b]pyrrole
• multicomponent reaction

An easy, highly efficient, and simple one-pot approach for the synthesis of dihyroindeno[1,2-b]pyrroles and indeno[2',1':4,5]pyrrolo[1,2-a]-fused 1,3-diazaheterocycles under mild conditions is reported. The reaction of a primary amine or 1,n-diamine with 1,1-bis(methylthio)-2-nitroethene in the presence of ninhydrin in aqueous media afforded the title compounds in good yields.

• 出版日期2011-2