A Ring Rearrangement Approach to the Synthesis of Benzo[b]quinolizine and Benzoindolizine Architectures

作者：Donaldson Lauren R; Haigh David; Hulme Alison N^*

来源：Synlett, 2009, 2009(10): 1587-1590.

DOI：10.1055/s-0029-1217338

• phenanthridine
• alkene
• ring-rearrangement metathesis
• flash vacuum pyrolysis
• skeletal diversity

An efficient ring rearrangement metathesis (RRM) approach to the synthesis of benzo[b]quinolizine and benzoindolizine systems from N-propargyl-phenanthridine derivatives is reported. A Hovel use of flash vacuum pyrolysis (FVP) for the Boc-deprotection of acid-sensitive substrates is also disclosed.

• 出版日期2009-6-17